File:Phylogenetic reconciliation summary.svg

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Summary

Description
English: Illustration of reconciliation events, inputs, outputs, and computational difficulties. Inputs are on the left of entries, output on the right. Upper trees are drawn in blue, lower trees in red.

This table is intended to serve as illustration to the 2-Level reconciliation section of Menet et al. (2022) Phylogenetic reconciliation. PLoS Comput Biol 18(11): e1010621. doi:10.1371/journal.pcbi.1010621 and can be read along it.

  • Adding the horizontal Transfer event adds new, more parsimonious solutions compared to the previous DL model (A).
  • With this new event, costs must be assigned to D,T and L events, and different costs give different solutions (B).
  • Not all scenarios including transfers are time feasible. Some might include time constraints incompatible with the upper tree (C).
  • Transfer can go from a species to one of its descendant via a sister lineages that went extinct (D).
  • In biogeography, a tree like structure can be constructed to account for the possible migrations between different geographical areas (E).
  • In some cases, an exponential number of scenarios might be most parsimonious, for example when two equivalent patterns have the same cost (F).
  • The lower tree can be
    • unrooted (G),
    • multifurcating (H), or
    • given as a sample of potential trees (I) and reconciliation can be used to resolve those uncertainties to get a binary rooted lower tree.
  • Reconciliation score can also be used to help construct an upper tree (J).
  • Dynamic programming is limited by the fact that it assumes independence between sister lineages, which makes it unable to consider
    • replacing transfers or gene conversion (K), as well as
    • Failure to diverge (L) and
    • Incomplete Lineage Sorting (M), two population level events.
Date
Source Own work
Author Hugo Menet

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Captions

Visual summary of phylogenetic reconciliation inputs, outputs, and computational difficulties.

Items portrayed in this file

depicts

18 May 2021

File history

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Date/TimeThumbnailDimensionsUserComment
current08:34, 20 December 2022Thumbnail for version as of 08:34, 20 December 20221,063 × 1,052 (202 KB)Daniel Mietchengrammar fix
08:21, 20 December 2022Thumbnail for version as of 08:21, 20 December 20221,063 × 1,052 (202 KB)Daniel Mietchentypo fix
16:00, 18 May 2021Thumbnail for version as of 16:00, 18 May 20211,063 × 1,052 (202 KB)HmenetFlowed text bug corrected
15:58, 18 May 2021Thumbnail for version as of 15:58, 18 May 20211,063 × 1,052 (217 KB)HmenetUploaded own work with UploadWizard
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